GFPT2

Entrez Summary: N/A
UniProt Summary: Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

SIS
GATase 2

glutamine-fructose-6-phosphate transaminase (isomerizing) activity
carbohydrate derivative binding
fructose 6-phosphate metabolic process
UDP-N-acetylglucosamine biosynthetic process
amino sugar biosynthetic process
UDP-N-acetylglucosamine metabolic process
glutamine metabolic process
nucleotide-sugar biosynthetic process
nucleotide-sugar metabolic process
amino sugar metabolic process
energy reserve metabolic process
glutamine family amino acid metabolic process
protein N-linked glycosylation
cellular response to leukemia inhibitory factor
response to leukemia inhibitory factor
alpha-amino acid metabolic process
energy derivation by oxidation of organic compounds
macromolecule glycosylation
protein glycosylation
glycosylation
cellular amino acid metabolic process
glycoprotein biosynthetic process
glycoprotein metabolic process
generation of precursor metabolites and energy
nucleobase-containing small molecule metabolic process
carbohydrate derivative biosynthetic process
organophosphate metabolic process
carboxylic acid metabolic process
oxidation-reduction process
oxoacid metabolic process
cellular response to cytokine stimulus
organic acid metabolic process
carbohydrate derivative metabolic process
nucleobase-containing compound biosynthetic process
response to cytokine
heterocycle biosynthetic process
aromatic compound biosynthetic process
organic cyclic compound biosynthetic process
organonitrogen compound biosynthetic process
cellular nitrogen compound biosynthetic process