GGTLC2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 633/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	24/28
blood	21/28
bone	23/26
breast	27/33
central nervous system	50/56
cervix	3/4
colorectal	15/17
esophagus	12/13
fibroblast	1/1
gastric	14/16
kidney	11/21
liver	16/20
lung	68/75
lymphocyte	13/16
ovary	24/26
pancreas	21/24
peripheral nervous system	15/16
plasma cell	11/15
prostate	1/1
skin	19/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	20/22
urinary tract	26/29
uterus	4/5

Expression Distribution

glutathione hydrolase activity
leukotriene D4 metabolic process
leukotriene D4 biosynthetic process
glutathione catabolic process
leukotriene biosynthetic process
cellular modified amino acid catabolic process
peptide catabolic process
leukotriene metabolic process
icosanoid biosynthetic process
sulfur compound catabolic process
glutathione metabolic process
cofactor catabolic process
fatty acid derivative biosynthetic process
icosanoid metabolic process
fatty acid derivative metabolic process
sulfur compound biosynthetic process
cellular modified amino acid metabolic process
carboxylic acid biosynthetic process
organic acid biosynthetic process
sulfur compound metabolic process
peptide biosynthetic process
cofactor metabolic process
drug metabolic process
amide biosynthetic process
peptide metabolic process
small molecule biosynthetic process
molecular function
cellular amide metabolic process
carboxylic acid metabolic process
oxoacid metabolic process
organic acid metabolic process
organonitrogen compound catabolic process
proteolysis
organonitrogen compound biosynthetic process
cellular nitrogen compound biosynthetic process
small molecule metabolic process
organic substance catabolic process
cellular catabolic process