GLTP

Entrez Summary: N/A
UniProt Summary: Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides. {ECO:0000269|PubMed:15329726, ECO:0000269|PubMed:15504043, ECO:0000269|PubMed:17980653, ECO:0000269|PubMed:18261224}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glycolipid transfer activity
lipid transfer activity
glycolipid binding
glycolipid transport
ceramide 1-phosphate binding
ceramide 1-phosphate transfer activity
ceramide 1-phosphate transport
intermembrane lipid transfer
ceramide transport
glycosphingolipid metabolic process
carbohydrate derivative transport
phospholipid transport
glycolipid metabolic process
liposaccharide metabolic process
organophosphate ester transport
lipid binding
sphingolipid metabolic process
membrane lipid metabolic process
lipid transport
lipid localization
organic anion transport
anion transport
membrane organization
cellular lipid metabolic process
carbohydrate derivative metabolic process
identical protein binding
lipid metabolic process
ion transport
amide transport
nitrogen compound transport