GNA14

Entrez Summary: N/A
UniProt Summary: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Arf
G-alpha

phospholipase C-activating dopamine receptor signaling pathway
G-protein beta/gamma-subunit complex binding
heterotrimeric G-protein complex
dopamine receptor signaling pathway
G protein-coupled receptor binding
cellular response to dopamine
response to dopamine
signal transduction involved in cellular response to ammonium ion
phospholipase C-activating G protein-coupled receptor signaling pathway
cellular response to catecholamine stimulus
cellular response to monoamine stimulus
response to catecholamine
response to monoamine
cellular response to ammonium ion
platelet activation
response to ammonium ion
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
blood coagulation
coagulation
hemostasis
GTPase activity
GTP binding
cellular response to drug
wound healing
regulation of body fluid levels
cellular response to organic cyclic compound
response to wounding
cellular response to organonitrogen compound
cellular response to nitrogen compound
response to organic cyclic compound
response to organonitrogen compound
response to drug
cellular response to oxygen-containing compound
cell activation
response to nitrogen compound
cellular response to endogenous stimulus
G protein-coupled receptor signaling pathway
response to endogenous stimulus
response to oxygen-containing compound