GRASP

Entrez Summary: N/A
UniProt Summary: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of endosome to plasma membrane protein transport
regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane
ADP-ribosylation factor binding
regulation of receptor localization to synapse
regulation of protein localization to synapse
Schaffer collateral - CA1 synapse
PDZ domain binding
regulation of protein localization to plasma membrane
regulation of protein localization to cell periphery
regulation of protein localization to membrane
postsynaptic membrane
regulation of intracellular protein transport
postsynaptic density
glutamatergic synapse
regulation of intracellular transport
regulation of cellular protein localization
cell junction
regulation of vesicle-mediated transport
perinuclear region of cytoplasm
regulation of protein transport
regulation of peptide transport
regulation of establishment of protein localization
regulation of cellular localization
regulation of protein localization
identical protein binding
regulation of transport