GRIN3B

Entrez Summary: N/A
UniProt Summary: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

ionotropic glutamate receptor activity
neurotransmitter binding
NMDA selective glutamate receptor complex
glycine binding
cation channel activity
ionotropic glutamate receptor signaling pathway
neurotransmitter receptor activity
protein insertion into membrane
glutamate receptor signaling pathway
calcium channel activity
calcium ion transmembrane transport
postsynaptic membrane
regulation of calcium ion transport
calcium ion transport
establishment of protein localization to membrane
divalent metal ion transport
divalent inorganic cation transport
neuronal cell body
regulation of metal ion transport
protein localization to membrane
cell junction
inorganic cation transmembrane transport
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
regulation of ion transport
cation transport
membrane organization
ion transmembrane transport
transmembrane transport
ion transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
regulation of transport