GRPEL2

• Official Symbol: GRPEL2
• Official Name: GrpE like 2, mitochondrial
• Aliases and Previous Symbols: N/A
• Entrez ID: 134266
• UniProt: Q8TAA5
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 16373
• Expression level (log2 read counts): 0.52

Expression Distribution

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GRPEL2 Expression in NALM6 Cells: 0.52