GSTK1

Entrez Summary: N/A
UniProt Summary: Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glutathione peroxidase activity
protein disulfide oxidoreductase activity
glutathione derivative biosynthetic process
glutathione derivative metabolic process
glutathione transferase activity
peroxisomal matrix
glutathione metabolic process
protein targeting to peroxisome
protein localization to peroxisome
establishment of protein localization to peroxisome
peroxisomal transport
peroxisome organization
intracellular
cellular oxidant detoxification
cellular detoxification
peroxisome
detoxification
sulfur compound biosynthetic process
cellular modified amino acid metabolic process
cellular response to toxic substance
protein targeting
sulfur compound metabolic process
mitochondrial matrix
establishment of protein localization to organelle
cofactor metabolic process
response to toxic substance
peptide metabolic process
epithelial cell differentiation
protein localization to organelle
cellular amide metabolic process
oxidation-reduction process
intracellular protein transport
epithelium development
mitochondrion
organonitrogen compound biosynthetic process
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization