GSTZ1

Gene Information

Official Symbol: GSTZ1
Official Name: glutathione S-transferase zeta 1
Aliases and Previous Symbols: N/A
Entrez ID: 2954
UniProt: O43708
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 15450
Expression level (log2 read counts): 3.81

Expression Distribution

GST N
GST C

maleylacetoacetate isomerase activity
tyrosine catabolic process
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of acyl-CoA biosynthetic process
tyrosine metabolic process
L-phenylalanine metabolic process
erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
L-phenylalanine catabolic process
erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
regulation of coenzyme metabolic process
regulation of sulfur metabolic process
glutathione peroxidase activity
glutathione derivative biosynthetic process
glutathione derivative metabolic process
aromatic amino acid family catabolic process
glutathione transferase activity
regulation of cofactor metabolic process
regulation of purine nucleotide biosynthetic process
aromatic amino acid family metabolic process
regulation of nucleotide biosynthetic process
glutathione metabolic process
regulation of fatty acid metabolic process
cellular oxidant detoxification
cellular detoxification
alpha-amino acid catabolic process
regulation of purine nucleotide metabolic process
regulation of nucleotide metabolic process
cellular amino acid catabolic process
detoxification
drug catabolic process
regulation of cellular ketone metabolic process
sulfur compound biosynthetic process
cellular modified amino acid metabolic process
alpha-amino acid metabolic process
cellular response to toxic substance
carboxylic acid catabolic process
organic acid catabolic process
cellular amino acid metabolic process
sulfur compound metabolic process
mitochondrial matrix