HBA1

Entrez Summary: N/A
UniProt Summary: Involved in oxygen transport from the lung to the various peripheral tissues.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

haptoglobin binding
organic acid binding
haptoglobin-hemoglobin complex
hemoglobin complex
oxygen carrier activity
oxygen transport
endocytic vesicle lumen
gas transport
hydrogen peroxide catabolic process
oxygen binding
peroxidase activity
hydrogen peroxide metabolic process
bicarbonate transport
cytosolic small ribosomal subunit
antibiotic catabolic process
cofactor catabolic process
cellular oxidant detoxification
cellular detoxification
antibiotic metabolic process
protein heterooligomerization
reactive oxygen species metabolic process
response to hydrogen peroxide
detoxification
iron ion binding
blood microparticle
heme binding
drug catabolic process
drug transport
response to reactive oxygen species
cellular response to toxic substance
receptor-mediated endocytosis
response to antibiotic
response to oxidative stress
cofactor metabolic process
organic anion transport
drug metabolic process
response to toxic substance
protein complex oligomerization
response to inorganic substance
endocytosis