HBD

Entrez Summary: N/A
UniProt Summary: Involved in oxygen transport from the lung to the various peripheral tissues.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

hemoglobin alpha binding
haptoglobin binding
haptoglobin-hemoglobin complex
organic acid binding
hemoglobin complex
oxygen carrier activity
oxygen transport
gas transport
hydrogen peroxide catabolic process
oxygen binding
peroxidase activity
hydrogen peroxide metabolic process
antibiotic catabolic process
cofactor catabolic process
cellular oxidant detoxification
cellular detoxification
antibiotic metabolic process
reactive oxygen species metabolic process
detoxification
heme binding
blood microparticle
drug catabolic process
drug transport
cellular response to toxic substance
blood coagulation
coagulation
hemostasis
cofactor metabolic process
wound healing
regulation of body fluid levels
drug metabolic process
response to toxic substance
response to wounding
response to drug
cellular catabolic process