HDDC3

Gene Information

Official Symbol: HDDC3
Official Name: HD domain containing 3
Aliases and Previous Symbols: N/A
Entrez ID: 374659
UniProt: Q8N4P3
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: ppGpp hydrolyzing enzyme involved in starvation response. {ECO:0000269|PubMed:20818390}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 4687
Expression level (log2 read counts): 3.5

Expression Distribution

guanosine tetraphosphate catabolic process
purine ribonucleoside bisphosphate catabolic process
guanosine tetraphosphate metabolic process
guanosine-3,5-bis(diphosphate) 3-diphosphatase activity
guanosine-containing compound catabolic process
nucleoside bisphosphate catabolic process
ribonucleoside bisphosphate catabolic process
purine nucleoside bisphosphate catabolic process
purine ribonucleoside catabolic process
purine nucleoside catabolic process
ribonucleoside catabolic process
purine ribonucleoside bisphosphate metabolic process
purine ribonucleotide catabolic process
ribonucleotide catabolic process
nucleoside catabolic process
guanosine-containing compound metabolic process
purine nucleotide catabolic process
glycosyl compound catabolic process
nucleobase-containing small molecule catabolic process
purine-containing compound catabolic process
purine ribonucleoside metabolic process
purine nucleoside metabolic process
nucleotide catabolic process
nucleoside phosphate catabolic process
ribonucleoside metabolic process
nucleobase-containing small molecule biosynthetic process
nucleoside metabolic process
organophosphate catabolic process
ribonucleoside bisphosphate metabolic process
nucleoside bisphosphate metabolic process
purine nucleoside bisphosphate metabolic process
glycosyl compound metabolic process
carbohydrate derivative catabolic process
purine ribonucleotide metabolic process
ribonucleotide metabolic process
purine nucleotide metabolic process
ribose phosphate metabolic process
purine-containing compound metabolic process
nucleobase-containing compound catabolic process
heterocycle catabolic process