HMX2

Entrez Summary: N/A
UniProt Summary: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of mRNA splicing, via spliceosome
positive regulation of mRNA processing
positive regulation of RNA splicing
positive regulation of mRNA metabolic process
inner ear morphogenesis
regulation of mRNA splicing, via spliceosome
ear morphogenesis
regulation of RNA splicing
regulation of mRNA processing
inner ear development
ear development
sensory organ morphogenesis
embryonic organ morphogenesis
regulation of mRNA metabolic process
sequence-specific DNA binding
embryonic organ development
sensory organ development
embryonic morphogenesis
brain development
head development
positive regulation of cell population proliferation
animal organ morphogenesis
embryo development
central nervous system development
DNA-binding transcription factor activity, RNA polymerase II-specific
regulation of cell population proliferation
positive regulation of RNA metabolic process
positive regulation of nucleobase-containing compound metabolic process
positive regulation of gene expression