IDI2

Entrez Summary: N/A
UniProt Summary: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). {ECO:0000269|PubMed:17202134}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

dimethylallyl diphosphate biosynthetic process
dimethylallyl diphosphate metabolic process
isopentenyl-diphosphate delta-isomerase activity
isopentenyl diphosphate metabolic process
isopentenyl diphosphate biosynthetic process
isoprenoid biosynthetic process
cholesterol biosynthetic process
secondary alcohol biosynthetic process
sterol biosynthetic process
hydrolase activity
peroxisome
alcohol biosynthetic process
cholesterol metabolic process
steroid biosynthetic process
secondary alcohol metabolic process
sterol metabolic process
isoprenoid metabolic process
organic hydroxy compound biosynthetic process
phospholipid biosynthetic process
steroid metabolic process
alcohol metabolic process
phospholipid metabolic process
organic hydroxy compound metabolic process
organophosphate biosynthetic process
lipid biosynthetic process
small molecule biosynthetic process
organophosphate metabolic process
cellular lipid metabolic process
lipid metabolic process
organic cyclic compound biosynthetic process
small molecule metabolic process