IFT43

• Official Symbol: IFT43
• Official Name: intraflagellar transport 43
• Aliases and Previous Symbols: N/A
• Entrez ID: 112752
• UniProt: Q96FT9
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a subunit of the intraflagellar transport complex A (IFT-A). IFT-A is a multiprotein complex that plays an important role in cilia assembly and maintenance by mediating retrograde ciliary transport. Mutations in this gene are a cause of cranioectodermal dysplasia-3 (CED3), also known as Sensenbrenner syndrome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
• UniProt Summary: Component of IFT complex A (IFT-A) involved in retrograde ciliary transport along microtubules from the ciliary tip to the base. {ECO:0000269|PubMed:21378380}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 17616
• Expression level (log2 read counts): 1.41

Expression Distribution

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IFT43 Expression in NALM6 Cells: 1.41