IFT46

Entrez Summary: N/A
UniProt Summary: Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

intraciliary transport particle B
intraciliary transport involved in cilium assembly
ciliary tip
intraciliary transport
microtubule-based protein transport
protein transport along microtubule
smoothened signaling pathway
motile cilium
ciliary basal body
transport along microtubule
cytoskeleton-dependent intracellular transport
protein stabilization
microtubule-based transport
protein C-terminus binding
cilium
protein-containing complex localization
microtubule-based movement
regulation of protein stability
cilium assembly
cilium organization
plasma membrane bounded cell projection assembly
cell projection assembly
centrosome
microtubule-based process
organelle assembly
molecular function
intracellular protein transport
plasma membrane bounded cell projection organization
cell projection organization
protein transport
intracellular transport
peptide transport
movement of cell or subcellular component
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
establishment of localization in cell
nitrogen compound transport