IGSF11

Entrez Summary: N/A
UniProt Summary: Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth. {ECO:0000269|PubMed:15795899, ECO:0000269|PubMed:16108831}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

I-set
V-set

positive regulation of mini excitatory postsynaptic potential
regulation of mini excitatory postsynaptic potential
positive regulation of long-term synaptic potentiation
positive regulation of excitatory postsynaptic potential
excitatory synapse
ionotropic glutamate receptor binding
modulation of excitatory postsynaptic potential
regulation of long-term synaptic potentiation
positive regulation of nervous system process
maintenance of protein location
regulation of nervous system process
positive regulation of synaptic transmission
maintenance of location
homophilic cell adhesion via plasma membrane adhesion molecules
cell-cell junction
regulation of synaptic plasticity
postsynaptic density
cell-cell adhesion via plasma-membrane adhesion molecules
regulation of membrane potential
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
cell-cell adhesion
regulation of system process
regulation of growth
cell adhesion
biological adhesion
positive regulation of signal transduction
positive regulation of multicellular organismal process
positive regulation of cell communication
positive regulation of signaling