IGSF9B

Entrez Summary: N/A
UniProt Summary: Transmembrane protein which is abundantly expressed in interneurons, where it may regulate inhibitory synapse development. May mediate homophilic cell adhesion. {ECO:0000250|UniProtKB:D3ZB51, ECO:0000250|UniProtKB:E9PZ19}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

postsynaptic specialization of symmetric synapse
positive regulation of inhibitory postsynaptic potential
modulation of inhibitory postsynaptic potential
inhibitory synapse
synaptic membrane adhesion
positive regulation of nervous system process
GABA-ergic synapse
kinase binding
regulation of nervous system process
positive regulation of synaptic transmission
homophilic cell adhesion via plasma membrane adhesion molecules
postsynaptic membrane
postsynaptic density
cell-cell adhesion via plasma-membrane adhesion molecules
synapse organization
neuronal cell body
dendrite
regulation of membrane potential
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
cell-cell adhesion
cell junction
regulation of system process
cell adhesion
biological adhesion
positive regulation of signal transduction
positive regulation of multicellular organismal process
positive regulation of cell communication
positive regulation of signaling