IL25

Entrez Summary: N/A
UniProt Summary: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

interleukin-5 production
interleukin-17E receptor binding
interleukin-13 production
response to nematode
eosinophil differentiation
cellular response to interleukin-17
response to interleukin-17
interleukin-17-mediated signaling pathway
granulocyte differentiation
inflammatory response to antigenic stimulus
response to fungus
myeloid leukocyte differentiation
cytokine production
cytokine activity
myeloid cell differentiation
leukocyte differentiation
inflammatory response
hemopoiesis
hematopoietic or lymphoid organ development
immune system development
cytokine-mediated signaling pathway
cellular response to cytokine stimulus
response to cytokine
positive regulation of transcription by RNA polymerase II
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
positive regulation of transcription, DNA-templated
extracellular space
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
cell development
positive regulation of RNA metabolic process
immune response
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
extracellular region
positive regulation of cellular biosynthetic process
positive regulation of gene expression