IL2RB

Entrez Summary: N/A
UniProt Summary: Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

interleukin-2 receptor complex
interleukin-2 receptor activity
interleukin-2 binding
interleukin-15 receptor activity
interleukin-2-mediated signaling pathway
cellular response to interleukin-2
response to interleukin-2
interleukin-15-mediated signaling pathway
cellular response to interleukin-15
response to interleukin-15
positive regulation of phagocytosis
regulation of phagocytosis
endosome
MAPK cascade
signal transduction by protein phosphorylation
external side of plasma membrane
regulation of vesicle-mediated transport
cell surface
cytokine-mediated signaling pathway
viral process
symbiotic process
interspecies interaction between organisms
negative regulation of apoptotic process
negative regulation of programmed cell death
protein phosphorylation
positive regulation of transport
negative regulation of cell death
cellular response to cytokine stimulus
response to cytokine
phosphorylation
integral component of plasma membrane
regulation of apoptotic process
protein-containing complex assembly
regulation of programmed cell death
regulation of cell death
intracellular signal transduction
protein-containing complex subunit organization
regulation of transport
membrane