IQCF1

Entrez Summary: N/A
UniProt Summary: Involved in sperm capacitation and acrosome reaction. {ECO:0000250|UniProtKB:Q9D9K8}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of flagellated sperm motility involved in capacitation
positive regulation of cilium-dependent cell motility
positive regulation of flagellated sperm motility
positive regulation of acrosome reaction
positive regulation of fertilization
regulation of flagellated sperm motility
regulation of acrosome reaction
regulation of cilium-dependent cell motility
sperm capacitation
regulation of fertilization
positive regulation of reproductive process
acrosomal vesicle
spermatid development
spermatid differentiation
cell maturation
regulation of reproductive process
calmodulin binding
developmental maturation
germ cell development
cellular process involved in reproduction in multicellular organism
positive regulation of multi-organism process
positive regulation of cell motility
positive regulation of cellular component movement
spermatogenesis
positive regulation of locomotion
male gamete generation
developmental process involved in reproduction
gamete generation
regulation of multi-organism process
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
regulation of cell motility
regulation of locomotion
multi-organism reproductive process
regulation of cellular component movement
reproductive process
reproduction
cell development