ISLR2

Entrez Summary: N/A
UniProt Summary: Required for axon extension during neural development. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of axon extension
positive regulation of axonogenesis
regulation of axon extension
regulation of extent of cell growth
positive regulation of cell morphogenesis involved in differentiation
positive regulation of cell growth
positive regulation of developmental growth
regulation of cell size
regulation of axonogenesis
positive regulation of growth
positive regulation of neuron projection development
regulation of cell morphogenesis involved in differentiation
regulation of developmental growth
positive regulation of neuron differentiation
regulation of cellular component size
positive regulation of cell projection organization
regulation of cell growth
positive regulation of neurogenesis
regulation of cell morphogenesis
regulation of neuron projection development
regulation of anatomical structure size
positive regulation of nervous system development
positive regulation of cell development
cell surface
regulation of neuron differentiation
regulation of growth
regulation of plasma membrane bounded cell projection organization
regulation of cell projection organization
regulation of neurogenesis
regulation of nervous system development
regulation of cell development
positive regulation of cell differentiation
regulation of anatomical structure morphogenesis
positive regulation of cellular component organization
positive regulation of developmental process
generation of neurons
neurogenesis
positive regulation of multicellular organismal process
regulation of cell differentiation