KCNK6

Entrez Summary: N/A
UniProt Summary: Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of resting membrane potential
potassium ion leak channel activity
stabilization of membrane potential
negative regulation of systemic arterial blood pressure
inward rectifier potassium channel activity
negative regulation of blood pressure
voltage-gated potassium channel complex
cardiac conduction
regulation of systemic arterial blood pressure
multicellular organismal signaling
potassium ion transmembrane transport
potassium ion transport
regulation of blood pressure
regulation of heart contraction
regulation of blood circulation
blood circulation
circulatory system process
monovalent inorganic cation transport
regulation of membrane potential
regulation of ion transmembrane transport
inorganic cation transmembrane transport
regulation of transmembrane transport
regulation of system process
cation transmembrane transport
metal ion transport
inorganic ion transmembrane transport
regulation of ion transport
cation transport
ion transmembrane transport
transmembrane transport
ion transport
integral component of plasma membrane
regulation of transport
system process