KIF19

Entrez Summary: N/A
UniProt Summary: Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cytoplasmic microtubule depolymerization
cilium disassembly
axonemal microtubule depolymerization
plus-end specific microtubule depolymerization
microtubule depolymerization
ATP-dependent microtubule motor activity, plus-end-directed
protein depolymerization
microtubule polymerization or depolymerization
kinesin complex
cytoplasmic microtubule organization
organelle disassembly
microtubule motor activity
axoneme
cellular protein complex disassembly
cilium
ATPase activity
microtubule binding
protein-containing complex disassembly
microtubule-based movement
microtubule
cilium organization
cellular component disassembly
supramolecular fiber organization
microtubule cytoskeleton organization
microtubule-based process
cytoskeleton organization
plasma membrane bounded cell projection organization
cell projection organization
ATP binding
movement of cell or subcellular component
protein-containing complex subunit organization