KLK15
Gene Information
- Official Symbol: KLK15
- Official Name: kallikrein related peptidase 15
- Aliases and Previous Symbols: N/A
- Entrez ID: 55554
- UniProt: Q9H2R5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
- UniProt Summary: Protease whose physiological substrate is not yet known.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 18449
- Expression level (log2 read counts): -3.8
KLK15 Expression in NALM6 Cells: -3.8
