KLRD1

Entrez Summary: N/A
UniProt Summary: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Rifampicin 30μM R08 exp430	-1.75
Rapamycin 1μM R00 exp29	1.8

MHC class Ib protein binding, via antigen binding groove
MHC class I protein complex binding
protein antigen binding
natural killer cell mediated immunity
transmembrane signaling receptor activity
carbohydrate binding
receptor complex
lymphocyte mediated immunity
external side of plasma membrane
innate immune response
leukocyte mediated immunity
defense response to other organism
immune effector process
regulation of immune response
response to other organism
response to external biotic stimulus
response to biotic stimulus
defense response
regulation of immune system process
immune response