KRTAP12-4

Gene Information
  • Official Symbol: KRTAP12-4
  • Official Name: keratin associated protein 12-4
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 386684
  • UniProt: P60329
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: N/A
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 4383
  • Expression level (log2 read counts): -7.68

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1