LAMP5

Entrez Summary: N/A
UniProt Summary: Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain. {ECO:0000250|UniProtKB:Q9D387}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

growth cone membrane
dendrite membrane
synaptic vesicle membrane
endoplasmic reticulum-Golgi intermediate compartment membrane
recycling endosome membrane
late endosome membrane
cytoplasmic vesicle membrane
early endosome membrane
endosome membrane
lysosomal membrane
establishment of protein localization to organelle
cell junction
protein localization to organelle
cellular protein localization
cellular macromolecule localization
establishment of protein localization