LHFPL2

Entrez Summary: N/A
UniProt Summary: Plays a role in female and male fertility. Involved in distal reproductive tract development. {ECO:0000250|UniProtKB:Q8BGA2}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of fertilization
platelet alpha granule membrane
regulation of fertilization
positive regulation of reproductive process
development of primary female sexual characteristics
female sex differentiation
platelet degranulation
development of primary male sexual characteristics
single fertilization
male sex differentiation
regulation of reproductive process
fertilization
development of primary sexual characteristics
sex differentiation
cellular component
positive regulation of multi-organism process
developmental process involved in reproduction
regulated exocytosis
molecular function
regulation of multi-organism process
exocytosis
sexual reproduction
multi-organism reproductive process
secretion by cell
export from cell
secretion
reproductive process
reproduction
vesicle-mediated transport