LRRC10

Entrez Summary: N/A
UniProt Summary: May play important roles in cardiac development and/or cardiac function. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Doxorubicin 0.02μM R08 exp478	-1.72
BI-2536 0.001μM R01 exp41	1.77

alpha-actinin binding
sarcomere
cardiac muscle cell development
cardiac cell development
cardiac muscle cell differentiation
cardiocyte differentiation
striated muscle cell development
muscle cell development
cardiac muscle tissue development
striated muscle cell differentiation
muscle cell differentiation
actin binding
striated muscle tissue development
muscle tissue development
cytoskeleton
muscle structure development
heart development
circulatory system development
mitochondrion
cell development
tissue development