LRRC34

Gene Information
  • Official Symbol: LRRC34
  • Official Name: leucine rich repeat containing 34
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 151827
  • UniProt: Q8IZ02
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. {ECO:0000250|UniProtKB:Q9DAM1}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 10966
  • Expression level (log2 read counts): 3.65

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1