LTBP3

• Official Symbol: LTBP3
• Official Name: latent transforming growth factor beta binding protein 3
• Aliases and Previous Symbols: N/A
• Entrez ID: 4054
• UniProt: Q9NS15
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010].
• UniProt Summary: May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM).

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 6389
• Expression level (log2 read counts): 3.86

Expression Distribution

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LTBP3 Expression in NALM6 Cells: 3.86