MAP1LC3B2

Gene Information
  • Official Symbol: MAP1LC3B2
  • Official Name: microtubule associated protein 1 light chain 3 beta 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 643246
  • UniProt: A6NCE7
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 7064
  • Expression level (log2 read counts): 3.02

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1