MAP1LC3C

• Official Symbol: MAP1LC3C
• Official Name: microtubule associated protein 1 light chain 3 gamma
• Aliases and Previous Symbols: N/A
• Entrez ID: 440738
• UniProt: Q9BXW4
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium (PubMed:23022382). May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins (PubMed:28404643). {ECO:0000269|PubMed:23022382, ECO:0000269|PubMed:28404643}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 17771
• Expression level (log2 read counts): 1.31

Expression Distribution

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MAP1LC3C Expression in NALM6 Cells: 1.31