MED22
Gene Information
- Official Symbol: MED22
- Official Name: mediator complex subunit 22
- Aliases and Previous Symbols: N/A
- Entrez ID: 6837
- UniProt: Q15528
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1788
- Expression level (log2 read counts): 6.8
MED22 Expression in NALM6 Cells: 6.8
