MEI1

Entrez Summary: N/A
UniProt Summary: Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity). {ECO:0000250|UniProtKB:Q9D4I2}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

meiotic telomere clustering
chromosome localization to nuclear envelope involved in homologous chromosome segregation
telomere localization
male meiosis I
male meiotic nuclear division
homologous chromosome segregation
chromosome organization involved in meiotic cell cycle
establishment of chromosome localization
chromosome localization
cell
meiotic chromosome segregation
meiosis I
meiosis I cell cycle process
spermatid development
meiotic nuclear division
spermatid differentiation
meiotic cell cycle process
nuclear chromosome segregation
meiotic cell cycle
germ cell development
chromosome segregation
nuclear division
organelle fission
cellular process involved in reproduction in multicellular organism
establishment of organelle localization
spermatogenesis
male gamete generation
organelle localization
developmental process involved in reproduction
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
cell cycle process
chromosome organization
cell cycle
reproductive process
reproduction
cell development