MEX3D

Entrez Summary: N/A
UniProt Summary: RNA binding protein, may be involved in post- transcriptional regulatory mechanisms. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

mRNA localization resulting in posttranscriptional regulation of gene expression
intracellular mRNA localization
mRNA 3-UTR AU-rich region binding
mRNA destabilization
RNA destabilization
positive regulation of mRNA catabolic process
positive regulation of mRNA metabolic process
negative regulation of translation
negative regulation of cellular amide metabolic process
regulation of mRNA stability
regulation of RNA stability
regulation of mRNA catabolic process
RNA localization
regulation of mRNA metabolic process
regulation of translation
positive regulation of cellular catabolic process
regulation of cellular amide metabolic process
positive regulation of catabolic process
posttranscriptional regulation of gene expression
perinuclear region of cytoplasm
regulation of cellular catabolic process
regulation of catabolic process
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
negative regulation of cellular macromolecule biosynthetic process
RNA binding
negative regulation of macromolecule biosynthetic process
negative regulation of cellular biosynthetic process
negative regulation of biosynthetic process
cellular macromolecule localization
negative regulation of gene expression
positive regulation of RNA metabolic process
positive regulation of nucleobase-containing compound metabolic process