MFSD8

Gene Information
  • Official Symbol: MFSD8
  • Official Name: major facilitator superfamily domain containing 8
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 256471
  • UniProt: Q8NHS3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq, Oct 2008].
  • UniProt Summary: May be a carrier that transport small solutes by using chemiosmotic ion gradients. {ECO:0000305}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 6364
  • Expression level (log2 read counts): 5.03

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1