MGAT4A

• Official Symbol: MGAT4A
• Official Name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
• Aliases and Previous Symbols: N/A
• Entrez ID: 11320
• UniProt: Q9UM21
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: N/A
• UniProt Summary: Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 17211
• Expression level (log2 read counts): 5.49

Expression Distribution

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MGAT4A Expression in NALM6 Cells: 5.49