MOXD1

Gene Information

Official Symbol: MOXD1
Official Name: monooxygenase DBH like 1
Aliases and Previous Symbols: N/A
Entrez ID: 26002
UniProt: Q6UVY6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 14263
Expression level (log2 read counts): -3.13

Expression Distribution

Cu2 monooxygen
DOMON
Cu2 monoox C

dopamine beta-monooxygenase activity
octopamine metabolic process
octopamine biosynthetic process
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
norepinephrine biosynthetic process
ethanolamine-containing compound metabolic process
dopamine catabolic process
catechol-containing compound catabolic process
catecholamine catabolic process
phenol-containing compound catabolic process
norepinephrine metabolic process
catechol-containing compound biosynthetic process
catecholamine biosynthetic process
cellular biogenic amine biosynthetic process
amine biosynthetic process
dopamine metabolic process
phenol-containing compound biosynthetic process
neurotransmitter biosynthetic process
catechol-containing compound metabolic process
catecholamine metabolic process
copper ion binding
cellular biogenic amine metabolic process
cellular amine metabolic process
amine metabolic process
organic hydroxy compound catabolic process
phenol-containing compound metabolic process
neurotransmitter metabolic process
secretory granule membrane
alcohol biosynthetic process
drug catabolic process
organic hydroxy compound biosynthetic process
ammonium ion metabolic process
alcohol metabolic process
regulation of neurotransmitter levels
aromatic compound catabolic process
organic hydroxy compound metabolic process
organic cyclic compound catabolic process
drug metabolic process
small molecule biosynthetic process
endoplasmic reticulum membrane