MRGPRE

Entrez Summary: N/A
UniProt Summary: Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Lapatinib 5μM R01 exp47	-1.96
Hippuristanol 0.12μM R08 exp489 no dilution day6	-1.7
Trientine 500μM R08 exp534	-1.7
Geldanamycin 0.01μM R05 exp235	1.85
Epigallocatechin gallate 20μM R05 exp230	2.04

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

7tm 1
7TM GPCR Srx

G protein-coupled receptor activity
G protein-coupled receptor signaling pathway