MYO18B

Entrez Summary: The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Myosin tail 1
Myosin head

unconventional myosin complex
cardiac muscle fiber development
filamentous actin
motor activity
muscle fiber development
cardiac muscle cell development
cardiac cell development
vasculogenesis
cardiac muscle cell differentiation
cardiocyte differentiation
Z disc
striated muscle cell development
muscle cell development
cardiac muscle tissue development
striated muscle cell differentiation
muscle cell differentiation
actin binding
striated muscle tissue development
muscle tissue development
in utero embryonic development
blood vessel morphogenesis
muscle structure development
blood vessel development
vasculature development
cardiovascular system development
heart development
chordate embryonic development
embryo development ending in birth or egg hatching
tube morphogenesis
tube development
circulatory system development
embryo development
ATP binding
cell development
tissue development