NAA38

Entrez Summary: N/A
UniProt Summary: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. {ECO:0000269|PubMed:19398576}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Aminopterin 0.005μM R07 exp335	-2.39
Diepoxybutane 3μM R07 exp354	-2
CyclicAMP 200μM R08 exp475	-1.98
OICR-9429 10μM R03 exp142	-1.81
Salinomycin 3.5μM R08 exp521	-1.77
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	-1.74
BI-D1870 2μM R04 exp162	1.71
Q15 1 to 2μM on day4 R04 exp164	1.81
Pyridostatin 4μM R05 exp240	2
MLN-4924 2μM R00 exp22	2.13
Temozolomide 200μM R04 exp189	2.31

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

NatC complex
polysome
negative regulation of apoptotic process
negative regulation of programmed cell death
negative regulation of cell death
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death