NAT6

Entrez Summary: N/A
UniProt Summary: Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. {ECO:0000269|PubMed:10644992}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

N-terminal peptidyl-aspartic acid acetylation
N-terminal peptidyl-glutamic acid acetylation
actin modification
peptidyl-aspartic acid modification
acetyl-CoA binding
N-acetyltransferase activity
peptide alpha-N-acetyltransferase activity
N-terminal protein amino acid acetylation
N-terminal protein amino acid modification
peptidyl-glutamic acid modification
protein acetylation
regulation of actin polymerization or depolymerization
regulation of actin filament length
protein acylation
protein maturation
regulation of actin filament organization
regulation of actin cytoskeleton organization
regulation of supramolecular fiber organization
regulation of cellular component size
regulation of actin filament-based process
actin cytoskeleton organization
regulation of anatomical structure size
regulation of cytoskeleton organization
actin filament-based process
peptidyl-amino acid modification
cytoskeleton organization
regulation of organelle organization
gene expression