NCAN

Entrez Summary: N/A
UniProt Summary: May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

dermatan sulfate biosynthetic process
dermatan sulfate metabolic process
chondroitin sulfate catabolic process
dermatan sulfate proteoglycan biosynthetic process
dermatan sulfate proteoglycan metabolic process
hyaluronic acid binding
chondroitin sulfate biosynthetic process
chondroitin sulfate proteoglycan biosynthetic process
chondroitin sulfate metabolic process
chondroitin sulfate proteoglycan metabolic process
sulfur compound catabolic process
glycosaminoglycan catabolic process
aminoglycan catabolic process
proteoglycan biosynthetic process
proteoglycan metabolic process
lysosomal lumen
Golgi lumen
glycosaminoglycan biosynthetic process
mucopolysaccharide metabolic process
aminoglycan biosynthetic process
glycosaminoglycan metabolic process
aminoglycan metabolic process
carbohydrate binding
sulfur compound biosynthetic process
monocarboxylic acid biosynthetic process
carbohydrate derivative catabolic process
extracellular matrix
carboxylic acid biosynthetic process
organic acid biosynthetic process
glycoprotein biosynthetic process
extracellular matrix organization
sulfur compound metabolic process
glycoprotein metabolic process
extracellular structure organization
skeletal system development
drug metabolic process
monocarboxylic acid metabolic process
small molecule biosynthetic process
carbohydrate derivative biosynthetic process
calcium ion binding