NCMAP

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Rotenone 20μM R00 exp34	-1.72
Hinokiflavone 12μM R08 exp487	1.71

peripheral nervous system myelin formation
structural constituent of myelin sheath
Schmidt-Lanterman incisure
paranode region of axon
positive regulation of myelination
myelin assembly
myelination in peripheral nervous system
peripheral nervous system axon ensheathment
Schwann cell development
Schwann cell differentiation
regulation of myelination
positive regulation of nervous system process
peripheral nervous system development
cellular component assembly involved in morphogenesis
myelination
glial cell development
axon ensheathment
ensheathment of neurons
regulation of nervous system process
glial cell differentiation
gliogenesis
positive regulation of nervous system development
regulation of system process
cellular component morphogenesis
anatomical structure formation involved in morphogenesis
regulation of nervous system development
positive regulation of developmental process
integral component of plasma membrane
neurogenesis
cell development
positive regulation of multicellular organismal process