NDRG2

Gene Information

Official Symbol: NDRG2
Official Name: NDRG family member 2
Aliases and Previous Symbols: N/A
Entrez ID: 57447
UniProt: Q9UN36
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 5798
Expression level (log2 read counts): 2.59

Expression Distribution

Abhydrolase 6
Ndr

regulation of platelet-derived growth factor production
regulation of vascular endothelial growth factor production
substantia nigra development
negative regulation of smooth muscle cell proliferation
neural nucleus development
negative regulation of ERK1 and ERK2 cascade
midbrain development
growth cone
regulation of smooth muscle cell proliferation
negative regulation of MAPK cascade
negative regulation of cytokine production
regulation of ERK1 and ERK2 cascade
Wnt signaling pathway
cell-cell signaling by wnt
negative regulation of protein phosphorylation
cell surface receptor signaling pathway involved in cell-cell signaling
negative regulation of phosphorylation
negative regulation of intracellular signal transduction
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process
negative regulation of protein modification process
negative regulation of cell population proliferation
regulation of cytokine production
perinuclear region of cytoplasm
brain development
regulation of MAPK cascade
molecular function
head development
central nervous system development
Golgi apparatus
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
cell-cell signaling
negative regulation of multicellular organismal process
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
regulation of protein phosphorylation
regulation of phosphorylation
regulation of cell population proliferation