NECAP1

• Official Symbol: NECAP1
• Official Name: NECAP endocytosis associated 1
• Aliases and Previous Symbols: N/A
• Entrez ID: 25977
• UniProt: Q8NC96
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].
• UniProt Summary: Involved in endocytosis. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 11564
• Expression level (log2 read counts): 5.3

Expression Distribution

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NECAP1 Expression in NALM6 Cells: 5.3