NIPAL4
Gene Information
- Official Symbol: NIPAL4
- Official Name: NIPA like domain containing 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 348938
- UniProt: Q0D2K0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene likely encodes a membrane receptor. Mutations in this gene have been associated with autosomal recessive congenital ichthyosis. [provided by RefSeq, Feb 2010].
- UniProt Summary: Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. {ECO:0000250, ECO:0000269|PubMed:15317751}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11286
- Expression level (log2 read counts): -1.76