NME9
Gene Information
- Official Symbol: NME9
- Official Name: NME/NM23 family member 9
- Aliases and Previous Symbols: N/A
- Entrez ID: 347736
- UniProt: Q86XW9
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: May be a regulator of microtubule physiology.
Pfam Domains GO Terms
Pfam Domains
| NDK |
| Thioredoxin |
GO Terms
| UTP biosynthetic process |
| UTP metabolic process |
| GTP biosynthetic process |
| CTP biosynthetic process |
| CTP metabolic process |
| guanosine-containing compound biosynthetic process |
| pyrimidine ribonucleoside triphosphate biosynthetic process |
| pyrimidine ribonucleoside triphosphate metabolic process |
| pyrimidine nucleoside triphosphate biosynthetic process |
| nucleoside diphosphate kinase activity |
| pyrimidine ribonucleotide biosynthetic process |
| pyrimidine nucleoside triphosphate metabolic process |
| ribonucleoside biosynthetic process |
| purine ribonucleoside biosynthetic process |
| purine nucleoside biosynthetic process |
| pyrimidine ribonucleotide metabolic process |
| GTP metabolic process |
| nucleoside biosynthetic process |
| guanosine-containing compound metabolic process |
| glycosyl compound biosynthetic process |
| purine ribonucleoside triphosphate biosynthetic process |
| purine nucleoside triphosphate biosynthetic process |
| pyrimidine nucleotide biosynthetic process |
| ribonucleoside triphosphate biosynthetic process |
| pyrimidine-containing compound biosynthetic process |
| nucleoside diphosphate phosphorylation |
| purine ribonucleoside triphosphate metabolic process |
| purine ribonucleoside metabolic process |
| pyrimidine nucleotide metabolic process |
| nucleotide phosphorylation |
| nucleoside triphosphate biosynthetic process |
| purine nucleoside metabolic process |
| ribonucleoside triphosphate metabolic process |
| purine nucleoside triphosphate metabolic process |
| ribonucleoside metabolic process |
| cell redox homeostasis |
| nucleoside diphosphate metabolic process |
| nucleoside triphosphate metabolic process |
| pyrimidine-containing compound metabolic process |
| nucleobase-containing small molecule biosynthetic process |
| nucleoside metabolic process |
| glycosyl compound metabolic process |
| purine ribonucleotide biosynthetic process |
| purine nucleotide biosynthetic process |
| ribonucleotide biosynthetic process |
| ribose phosphate biosynthetic process |
| purine-containing compound biosynthetic process |
| nucleotide biosynthetic process |
| nucleoside phosphate biosynthetic process |
| purine ribonucleotide metabolic process |
| ribonucleotide metabolic process |
| purine nucleotide metabolic process |
| ribose phosphate metabolic process |
| cytoskeleton |
| purine-containing compound metabolic process |
| nucleotide metabolic process |
| nucleoside phosphate metabolic process |
| organophosphate biosynthetic process |
| nucleobase-containing small molecule metabolic process |
| small molecule biosynthetic process |
| carbohydrate derivative biosynthetic process |
| organophosphate metabolic process |
| cellular homeostasis |
| carbohydrate derivative metabolic process |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| phosphorylation |
| organic cyclic compound biosynthetic process |
| organonitrogen compound biosynthetic process |
| cellular nitrogen compound biosynthetic process |
| homeostatic process |
| small molecule metabolic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Trichostatin-A 0.06μM R07 exp415 | -1.74 |
| Fas-L 44ng/ml R08 exp482 | -1.71 |
| Rapamycin 1μM R00 exp29 | 2.71 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 9492
- Expression level (log2 read counts): 1.96
Expression Distribution
NME9 Expression in NALM6 Cells: 1.96
